Project Overview +

Despite major scientific advances, heart failure continues to be a common and costly condition, and each year more than 1 million people are admitted to an inpatient setting for acute heart failure. There is an urgent need for low-cost solutions to reduce morbidity in heart failure. 

Several studies have shown that self-monitoring can improve quality of life in heart failure patients. Self-monitoring includes daily tracking of symptoms, weight, and exercise. Accurate self-monitoring, feedback and self-efficacy (an individualís belief in their ability to perform a specific behavior) are essential components of the self-regulation cycle and are critical for managing heart failure. 

ManageHF4Life is a mobile application designed to promote self-monitoring and self-management of heart failure. Behavior change interventions that focus on self-regulation are particularly well suited for automation. The use of technology can decrease the burden of self-monitoring and enhance self-regulatory efforts. Cyclical processes of goal setting, behavior change, and goal assessment can be easily tracked, charted, reviewed and automated.

Related Media +

Related Media:

Aims +

Aim 1: Determine the impact of a self-monitoring mobile heart failure application on (1) self-management, (2) quality of life, and (3) hospital admission in ambulatory heart failure patients.

Aim 2: Determine the extent to which passive pre-clinical measurements predict symptoms of clinical worsening of heart failure.

Aim 3: Develop a notification message system for the mobile application to improve self-management of heart failure via patient participant feedback.

Participants +

All patients enrolled in the 2 phases of research will be greater than 45 years old and have a left ventricular ejection fraction <40%. Patients will be excluded for any of the following: unstable coronary syndromes within the 8 weeks of enrollment, primary valvular heart disease, primary myocardial disease, pericardial disease, uncorrected thyroid disease, advanced renal disease (dialysis or creatinine >4.0 mg/dL), end-stage heart failure (hospice candidate), active cancer, pulmonary fibrosis, discharge to a setting other than home, or requirement for chronic inotropic therapy.

Intervention +

Phase 1 is a clinical study to determine the effects of the mobile application and the predictability of passive pre-clinical measurements on clinical worsening in ambulatory heart failure patients. The app adapts to patientsí reported symptoms and provides feedback with a global health indicator.


Phase 2 will establish an adaptive notification message system based on the patientís passive self-monitoring and deliver notifications (i.e. behavioral interventions) to increase self-management.


01/01/2017 - 01/31/2019

Principal Investigator:

Mike Dorsch


Scott Hummel MD MS
Todd Michael Koelling M.D.